I can't be the only one to have played and loved this awesome PS2 game.
It's about a girl named Fiona who gets in a car accident while traveling with her family during college break. After witnessing the deaths of her parents, the last thing she sees before losing consciousness is a mysterious, shadowy figure reaching in the car for her. An undetermined amount of time later, she awakens in a dank basement that stinks of rotten meat, watched over by a deformed, hulking brute.
She manages to escape her cage, but her freedom is only as good as she can outrun her captors...
Bit dramatic there, ha. Simply put, the game is a lot like Clock Tower in that you run away from pursuers and have a Panic Meter. You have a dog named Hewie who will help you in combat and in finding things, which is similar to Rule of Rose. The plot is very intriguing, and the gameplay is hella fun. The pursuers are all scary as all get-out, and Fiona herself is likable enough that you'll find yourself really, really wanting to save and protect her.
If you haven't played it, I highly, highly recommend it.